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Technical Seminar: Theory & Application

Presented By: Applexion

About the Course

November 1st-2nd, 2023

Course Information:

Seminar Day #1: Ceramic Membrane Filtration

November 1, 2023

The AM session will focus on the basic theory behind the technology including common terms and definitions, brief history of ceramic membranes, basic flow process, how separation occurs, modes of operation, pore size selection, and how to size a system. The PM session will focus on the implementation of ceramic membranes in industrial plants including pilot testing, scaling up, installation/ commissioning/operation of a system, and typical maintenance and troubleshooting guidelines.

Speaker:

Hafedh Sadani, PhD

CPL Manager, Membrane Process Expert

AM SESSION

PART 1 – 9AM to 10:15AM

• Membranes: Terms and Definitions
• Ceramic Membranes: Manufacturing, properties, strengths & weaknesses
• Kerasep Membranes: Geometries, pore sizes & configurations

Morning break

PART 2 – 10:30AM to 12PM

• Membrane Filtration Process: Terms and Definitions (recovery, VCF, diafiltration, etc.)
• Membrane System: System assembly, system configuration, batch, fed-batch, etc.
• Equipment and Control: Process control, CIP, backpulse, utility recovery, etc.

LUNCH TIME – 12PM to 1PM

PM SESSION

PART 1 – 1PM to 2:30PM

• Ceramic Membrane Selection: Pore size and geometry
• Scaling Up: Implementation from pilot testing to the industrial plant
• Pilot Testing Case Study: Clarification (MF) and concentration (UF) of enzyme broth

Afternoon break

PART 2 – 2:45PM to 4:00PM

• Industrial System: Case studies (batch, fed batch, cont. system), process design & performances
• Industrial System: Troubleshooting Guidelines

Evening Reception at  Triptych Brewing

Seminar Day #2: Continuous Industrial Chromatography

November 2, 2023

The AM session will focus on the basic theory behind the technology including common terms and definitions, evolution of industrial chromatography, basic flow process, physico-chemical interactions, how separation occurs, modes of operation, resin selection, and how to size a system. The PM session will focus on the implementation of this technology in industrial plants including pilot testing, scaling up, installation/ commissioning/operation of a system, and typical maintenance and troubleshooting guidelines.

Speaker:

Hector Osuna, PhD

R&D Manager, Chromatography Process Expert

 

AM SESSION

PART 1 – 9AM to 10:30AM

• Brief introduction to chromatography
• Deep journey into the theory: Chemical and physical interactions, main equations & design implications

Morning break

PART 2 – 10:45AM to 12PM

• list text hereScale-up: From lab to Industrial (Defining CAPEX and OPEX from trials)
• list text hereBatch Chromatography to Continuous Chromatography

LUNCH TIME 12PM-1PM

PM SESSION

PART 1 – 1PM to 2:30PM

• Industrial Design: Process design and industrial equipment
• System Operation: Separations zones, parameter setting, operation sequences

Afternoon break

PART 2 – 2:45PM to 4PM – Troubleshooting : What if purity and yield targets are not met ? What if water consumption is too high? What if there is increasing pressure drop? Etc.

General Information

Contacts:

Amy Rogers arogers9@illinois.edu

Beth Conerty bconerty@illinois.edu

Location: The Integrated Bioprocessing Research Laboratory 1300 W. Pennsylvania Ave Urbana, IL 61801

Meals: Light Breakfast and Lunches will be provided. There is an optional evening reception on Wednesday, food and beverages will be provided.

Hotel: IBRL has reserved a block of hotel rooms at the iHotel (https://go.illinois.edu/iHotel), which are available on a first come, first serve basis. Shuttle transportation will be provided to and from the I-Hotel and the course events. To make your reservation, please go to https://go.illinois.edu/booking and use Block Code: IBRLOCT23 and password: i@F8c You may also call the I-Hotel directly at 217-819-500 and mention the hotel Block Code IBRLOCT23.

Transportation: A shuttle will be provided between the hotel and course location. The shuttle will also transport participants to and from the Wednesday evening reception.