Important Information
Course Dates: June 9-11
Course Fee: $700/day
Location: The Integrated Bioprocessing Research Laboratory 1300 W. Pennsylvania Ave Urbana, IL 61801
Meals: Light Breakfast and Lunches will be provided. There is an optional evening reception on Tuesday, food and beverages will be provided.
Hotel: IBRL has reserved a block of hotel rooms at the Holiday Inn Champaign. You can make a reservation by May 9, by calling (217) 398-3400 or by using this booking link.
Transportation: A shuttle will be provided between the hotel and course location. The shuttle will also transport participants to and from the Tuesday evening reception.
Agenda
Day 1: Chromatography Technology & Applications
The AM session will focus on the basic theory behind the technology, including common terms and definitions, evolution of industrial chromatography, basic flow process, physico-chemical interactions, how separation occurs, modes of operation, resin selection, and how to size a system. The PM session will focus on the implementation of this technology in industrial plants, including pilot testing, scaling-up, installation/commissioning/operation of a system, as well as typical maintenance and troubleshooting guidelines. It will also include new digital tools presentation for day-to-day operational optimization and digital platforms demonstration (dashboards, data management, etc.).
Speakers:
Quentin Sanlaville
R&D Project Manager & Partnerships
Antoine Charbonneau
Process & Sales Manager, American Team
PART 1 – 9AM to 10:30AM
- Introduction to Chromatography.
- Deep journey into the theory: chemical & physical interactions, main equations & design implications.
Morning break
PART 2 – 10:45AM to 12PM
- Scale-Up: from lab to industrial scale (defining CAPEX and OPEX from trials).
- Batch Chromatography to Continuous Chromatography.
LUNCH TIME 12PM-1PM
PM SESSION
PART 1 – 1PM to 3:00PM
- Industrial Design: Process design & industrial equipment.
- System Operation: Separation zones, parameters setting, operation sequences, troubleshooting guidelines.
- Case studies: Sugars & Sweeteners, Organic Acids.
Afternoon break
PART 2 – 3:15PM to 4:45PM
- Presentation of the Chromatography pilot unit.
- Use of Run4.0 & Perform4.0 Digital Tools platform to speed-up R&D, secure scale-up, ensure commissioning, and maintain Equipment at the right Performance.
Evening Reception at Triptych Brewing
Day 2: Ion Exchange Technology & Applications
The AM session will focus on the basic theory behind the technology, including common terms and definitions, evolution of industrial ion exchange, basic flow process, physico-chemical interactions, how purification occurs, modes of operation, resin selection, and how to size a system. The PM session will focus on the implementation of this technology in industrial plants, including pilot testing, scaling-up, installation/commissioning/operation of a system, as well as typical maintenance and troubleshooting guidelines. It will also include typical case studies review.
Speakers:
Quentin Sanlaville
R&D Project Manager & Partnerships
Antoine Charbonneau
Process & Sales Manager, American Team
AM SESSION
PART 1 – 9AM to 10:30AM
- Introduction to Ion Exchange.
- Deep journey into the theory: chemical & physical interactions, design implications.
Morning break
PART 2 – 10:45AM to 12PM
- Scale-Up: from lab to industrial scale (defining CAPEX and OPEX from trials).
- Ion Exchange Resin Types & Applications.
LUNCH TIME 12PM-1PM
PM SESSION
PART 1 – 1PM to 2:30PM
- Industrial Design: Process design & industrial equipment.
- System Operation: Pressure vessels improvements, recycling, troubleshooting guidelines.
Afternoon break
PART 2 – 2:45PM to 4:45PM – Case studies: Sugars & Sweeteners, Amino Acids, Proteins.
- Presentation of Ion Exchange pilot unit.
- Use of Run4.0 Digital Tool platform to turn your live process data into fast, reliable, and industrially actionable decisions.
- Case studies: Sugars & Sweeteners, Amino Acids, Proteins.
Day 3: Membrane Filtration Technology & Applications
Thursday June 11, 2026
The AM session will focus on the basic theory behind the technology, including common terms and definitions, brief history of ceramic membranes, basic flow process, physico-chemical interactions, how separation occurs, modes of operation, pore size selection, how to size a system, as well as on pilot testing and scaling-up through case study.
The PM session will focus on the implementation of this technology in industrial plants, installation/commissioning/operation of system, equipment and controls, typical maintenance and troubleshooting guidelines, as well as on polymeric membrane and Complete Process Line case study. It will also include a ceramic membrane filtration pilot demonstration.
Frederic Buisan
Process & Operations Manager
Antoine Charbonneau
Process & Sales Manager, American Team
AM SESSION
PART 1 – 9AM to 10:30AM
- Membrane Terms and Definitions.
- Ceramic Membranes: Manufacturing, properties, strengths & weaknesses, geometries, pore sizes & configurations.
- Membrane Filtration Process & System: Terms & definitions (Recovery, VCF, diafiltration, etc.), assembly, configurations, batch, fed-batch, etc.
Morning break
PART 2 – 10:45AM to 12PM
- Ceramic Membrane Selection: Pore size & geometry.
- Polymeric membrane (UF, NF).
- Case Study: Scaling-Up from pilot testing to the industrial plant.
LUNCH TIME – 12PM to 1PM
PM SESSION
PART 1 – 1PM to 2:15PM
- Equipment & Control: Process control, CIP, backpulse, utility recovery, etc.
- Troubleshooting guidelines.
Afternoon break
PART 2 – 2:30PM to 4:30PM
- Presentation of Micro-Kerasep and K01 ceramic membrane filtration pilot units.
- Hands-on activity around the K01 pilot.
- Use of Run4.0 Digital Tool platform to turn your live process data into fast, reliable, and industrially actionable decisions.
5:00PM-5:15PM- Certificates and Group Photo
About the Speakers:
Frédéric Buisan
Process & Operations Manager
Frédéric Buisan is a seasoned Process & Operations Manager based in the Lyon area, France, with over 15 years of experience in industrial process engineering. A chemical engineer by training, he has strong expertise in process design, project execution, plant commissioning, and start-up.
He joined Applexion in 2012 as a process engineer, working across key purification technologies, including chromatography, ion exchange, and membrane filtration. Over the years, he has contributed to the optimization and successful delivery of numerous complex industrial projects.
Since 2021, Frédéric has served as the technical lead for all process-related topics on ongoing projects, providing guidance and oversight to project teams. He also acts as a recognized technical reference for membrane-related technologies, supporting projects with his in-depth expertise.
He has led multiple international plant start-ups, coordinating multidisciplinary teams and ensuring reliable project execution. Frédéric is committed to knowledge sharing and team development, supporting the transfer of expertise and best practices across the organization.
Antoine Charbonneau
Process & Sales Manager, American Team
Antoine Charbonneau is Process & Sales Manager for the American team, based in Denver, CO. He has been working for Applexion over the Americas region for more than 7 years, specializing in various markets including Food, Functional ingredient and Bio industries (Fermentation) activities. Prior to that, he worked for several years as Process Engineer in Shanghai, China where he designed and engineered number of projects in the field of biotech and food & beverage, either for complete turnkey plants, or specific purification process units. He also published scientific articles in international reviews such as the Sugar Journal and participated to number of R&D developments, some of which having been patented. Antoine is current and former member of Sugar Industry Technologists, American Society of Sugar Cane Technologists, and American Dairy Product Institute. He holds a position as a board member in several technical sub commitees of these associations.
Quentin Sanlaville
R&D Project Manager & Partnerships
Quentin is R&D Project Manager & Partnerships. He has a chemical engineering degree from ESCOM Engineering School (Compiègne, France). He gained a strong background in biomolecule valorization, notably through his process engineering specialization at LUT (Lappeenranta, Finland). He joined APPLEXION after two years in a start-up to develop a GOS production line from agricultural residue. In 2018, he started to work at APPLEXION as part of the Research and Development team, working on industrial purification process developments. He has been involved in various projects related to resins and membranes with a focus on chromatography research at laboratory and pilot scale. At the same time, he actively contributes to the expertise concerning the numerical simulation approach, especially for chromatography users. He has taken the lead since 2024 regarding the R&D partnerships to accelerate project development at customer site and ensure project scale-up based on APPLEXION methodology.